; ============================================= DESCRIPTION: PK model Simple linear one compartment PK model with 1st order absorption. ; ============================================= [LONGITUDINAL] input = {ka,CL,Vc} ; ============================================= PK: ; ============================================= ; Model parameters ; ---------------- Tlag1 = 0 ; (hour) Lagtime for INPUT1 ; Model compartments ; ------------------ compartment(cmt=1, amount=Ac) ; Model dosing ; ------------ absorption(cmt=1, type=1, ka=ka, p=1, Tlag=Tlag1) ; Transfer and elimination definitions ; ------------------------------------ elimination(cmt=1, k=-(-(CL/Vc))) ; Output variables ; ---------------- Cc = Ac/Vc ; ============================================= OUTPUT: ; ============================================= output = {Cc}