********** MODEL NAME PK model ********** MODEL NOTES Simple linear one compartment PK model with 1st order absorption. ********** MODEL STATES d/dt(Ad) = -ka*Ad + INPUT1 d/dt(Ac) = ka*Ad - CL/Vc*Ac ********** MODEL PARAMETERS ka = 1 # (1/hour) Absorption rate CL = 3 # (L/hour) Apparent clearance Vc = 60 # (L) Apparent volume of distribution Tlag1 = 0 # (hour) Lagtime for INPUT1 Tk0 = 0 # (hour) Zero order absorption rate for INPUT1 ********** MODEL VARIABLES Cc = Ac/Vc OUTPUT1 = Cc # Plasma concentration ********** MODEL REACTIONS ********** MODEL FUNCTIONS ********** MODEL EVENTS