Preface
- Who this book is for
- How to read this book
I Introduction
1 License and Availability
- 1.1 Source Code
2 Requirements
3 Installation
- 3.1 IQR Tools
- 3.2 Setup after installation
4 Examples in this Book
- 4.1 Public version IQR Tools
- 4.2 Versioned IQR Tools
5 Reproducibility of Results
6 Validation
- 6.1 Validation of IQR Tools
- 6.2 Validation support
7 Release Notes
II Case Studies
8 Analysis dataset preparation
- 8.1 Example workflow
- 8.2 Workflow customization
9 Model definition
10 Simulation of models
11 NLME Modeling
12 QSP Modeling
13 Model evaluation
14 Advanced modeling workflows
15 Population simulations
- 15.1 Basic population simulation
- 15.2 Clinical trial simulation
  - 15.2.1 Parallel design example
  - 15.2.2 Adaptive design example
16 Experimental design
- 16.1 Use of PopED
  - 16.1.1 PopED / IQR Toolsinterface
  - 16.1.2 Same example in PopED
- 16.2 Use of profile likelihood
17 Exposure response analysis
18 Reporting in Microsoft Word
- 18.1 Example analysis report
- 18.2 Applying styles when creating Word document
III Manuals
19 General Dataset Format
20 Structural Model Syntax
21 Dosing definition
- 21.1 IQRdosing object
22 General Parameter Format (GPF)
23 Random sampling of NLME model parameters
Appendix
A Function Reference
(c) 2018-2020 IntiQuan GmbH

1 License and Availability

IQR Tools is available as an Open Source R package and published under the GNU Affero General Public License, Version 3.

1.1 Source Code

Download the source code: from here.