Extends the model specification by covariate relationships.
addCovariateToModelSpec_IQRest.RdCan be used for syspharm and NLME type of estimation objects. This is a convenience function to ease the extension of model specification by covariate relationships taking care of the entries for 'covariateModel', 'COVestimate', 'COVcentering', and 'covariateModelValues'
addCovariateToModelSpec_IQRest(modelSpec, covariateModel, covariateModelValues = NULL, COVestimate = NULL, COVcentering = NULL)
Arguments
| modelSpec | Model specification to be extended. |
|---|---|
| covariateModel | Named list with covariate relationships to be added. |
| covariateModelValues | Optional named list with initial covariate values |
| COVestimate | Optional named list with flags whether to estimate the respective covariate relationship |
| COVcentering | Optional named vector with reference values for covariates (will only be applied for non-existing reference values) |
Value
Returns modified model specification.
See also
Other IQRnlmeProject: IQRnlmeEst,
IQRnlmeProject,
addPar_modelSpec,
as_IQRnlmeProjectMulti,
as_IQRnlmeProject,
bootstrap_IQRnlmeProject,
compareModels_IQRnlmeProjectMulti,
convertETAINDIVPRED_IQRnlmeProject,
covariateEffect_IQRnlmeProject,
createDataVPC_IQRnlmeProject,
data_IQRest, dosing_IQRest,
duplicate_IQRnlmeProject,
eigenvalues_IQRnlmeProject,
exportVirtualSubjects_IQRnlmeProject,
getData_IQRnlmeProject,
getETAs_IQRnlmeProject,
getEst_IQRnlmeProject,
getHeader_IQRnlmeProject,
getIndivParameters_IQRnlmeProject,
getIndivPredictions_IQRnlmeProject,
getModel_IQRnlmeProject,
getObsPred_IQRnlmeProject,
getPopParameters_IQRnlmeProject,
getResults_IQRnlmeProjectMulti,
getResults_IQRnlmeProject,
hasrun_IQRnlmeProjectMulti,
hasrun_IQRnlmeProject,
informationContent_IQRnlmeProject,
is_IQRnlmeEst,
is_IQRnlmeProjectMulti,
is_IQRnlmeProject,
is_MONOLIX_IQRnlmeProject,
is_NLMIXR_IQRnlmeProject,
is_NONMEM_IQRnlmeProject,
modelSpec_IQRest,
outlier_IQRnlmeProject,
plot.IQRnlmeProjectMulti,
plot.IQRnlmeProject,
plotConvergence_IQRnlmeProject,
plotETACOV_IQRnlmeProject,
plotETA_IQRnlmeProject,
plotGOF_IQRnlmeProject,
plotINDIVSIM_IQRnlmeProject,
plotINDIV_IQRnlmeProject,
plotVPC_IQRdataVPC,
pred_IQRnlmeProject,
print.IQRnlmeEst,
print.IQRnlmeProjectMulti,
print.IQRnlmeProject,
print_modelSpec,
run_IQRnlmeProjectMulti,
run_IQRnlmeProject,
sample_IQRnlmeProject,
summary.IQRnlmeProjectMulti,
summary.IQRnlmeProject,
summaryComments_IQRnlmeProjectMulti,
summaryCorrelations_IQRnlmeProjectMulti,
summaryCovariates_IQRnlmeProjectMulti,
summaryParameters_IQRnlmeProjectMulti,
vpc_IQRnlmeProject
Examples
if (FALSE) { # Model specification with one covariate relationship modelSpec0 <- list( POPvalues = c(ka = 0.1, CL = 1, Vc = 20), covariateModel = list(CL = "BWT") ) # Add covariate model with initial guess modelSpec1 <- addCovariateToModelSpec_IQRest( modelSpec = modelSpec0, covariateModel = list(Vc = "SEX"), covariateModelValues = list(Vc = c("SEX" = 0.5)) ) }