Determines eigenvalues of an NLME project

Useful function to determine the terminal elimination halflife for PK models. It currently only works for linear models. In case of non-linear models or models for which not all parameters are defined NA will be returned.

eigenvalues_IQRnlmeProject(
  projectPath,
  Nsamples = NULL,
  FLAGiiv = TRUE,
  covariates = NULL
)

Arguments

projectPath

Path to the NLME project

Nsamples

If NULL, the eigenvalues for the population mean parameters are returned. If a number is provided, samples are taken from the distribution and for each realization the eigenvalues are returned. The distribution from which sampling is done is determined by FLAGiiv argument.

FLAGiiv

If TRUE (default) then the sample are drawn from the intr-individual variability distribution. If FALS then samples are drawn from the uncertainty distribution of the population mean parameters.

covariates

Data frame with covariates that will be taken into account when sampling also from IIV

Value

data.frame with eigenvalues

See also

Other IQRnlmeProject: IQRnlmeEst(), IQRnlmeProject(), addCovariateToModelSpec_IQRest(), addPar_modelSpec(), as_IQRnlmeProject(), as_IQRnlmeProjectMulti(), bootstrap_IQRnlmeProject(), compareModels_IQRnlmeProjectMulti(), convertETAINDIVPRED_IQRnlmeProject(), covariateEffect_IQRnlmeProject(), data_IQRest(), dosing_IQRest(), duplicate_IQRnlmeProject(), exportVirtualSubjects_IQRnlmeProject(), getData_IQRnlmeProject(), getETAs_IQRnlmeProject(), getEst_IQRnlmeProject(), getHeader_IQRnlmeProject(), getIndivParameters_IQRnlmeProject(), getIndivPredictions_IQRnlmeProject(), getModel_IQRnlmeProject(), getObsPred_IQRnlmeProject(), getPopParameters_IQRnlmeProject(), getResults_IQRnlmeProject(), getResults_IQRnlmeProjectMulti(), hasrun_IQRnlmeProject(), hasrun_IQRnlmeProjectMulti(), informationContent_IQRnlmeProject(), is_IQRnlmeEst(), is_IQRnlmeProject(), is_IQRnlmeProjectMulti(), is_MONOLIX_IQRnlmeProject(), is_NLMIXR_IQRnlmeProject(), is_NONMEM_IQRnlmeProject(), modelSpec_IQRest(), outlier_IQRnlmeProject(), plot.IQRnlmeProject(), plot.IQRnlmeProjectMulti(), plotBLQVPC_IQRdataVPC(), plotConvergence_IQRnlmeProject(), plotETACOV_IQRnlmeProject(), plotETA_IQRnlmeProject(), plotGOF_IQRnlmeProject(), plotINDIVSIM_IQRnlmeProject(), plotINDIV_IQRnlmeProject(), plotMEANSIM_IQRnlmeProject(), plotVPC_IQRdataVPC(), pred_IQRnlmeProject(), print.IQRnlmeEst(), print.IQRnlmeProject(), print.IQRnlmeProjectMulti(), print_modelSpec(), run_IQRnlmeProject(), run_IQRnlmeProjectMulti(), sample_IQRnlmeProject(), scm_IQRnlmeProject(), summary.IQRnlmeProject(), summary.IQRnlmeProjectMulti(), summaryComments_IQRnlmeProjectMulti(), summaryCorrelations_IQRnlmeProjectMulti(), summaryCovariates_IQRnlmeProjectMulti(), summaryParameters_IQRnlmeProjectMulti(), vpc_IQRnlmeProject()